Ranexa is an anti-anginal (chest pain) drug. Angina is a pain that comes from the heart. It is usually due to narrowing of the arteries that supply blood to our heart. This narrowing reduces the blood supply to parts of your cardiac muscle. The blood and oxygen demanded by heart then it can get through the narrowed arteries (for eg; when you walk fast or climb stairs), you feel chest pain. It improves blood flow to the heart hence, the heart function more efficiently. It is a drug of choice to treat chronic chest pain (angina). Ranexa is not for use during an acute (emergency) attack of angina.

Ranexa is taken in addition to other medicines used to prevent chest pain. The doctor prescribes this medicine if the other anti-anginal drugs do not sufficiently control your chest pain. Do not take Ranexa to treat a sudden attack of angina. Your doctor will tell you what you should do if you experience an attack of angina. Make sure that you understand these directions.

Ranexa may help control your condition but will not cure it. Continue to take Ranexa even if you feel well. Do not stop taking Ranexa without talking to your doctor. It is manufactured by Gilead sciences.

Ranexa composition and active ingredients:

Raxena drug is composed of the following active ingredients

  • In each tablet Ranolazine is an active ingredient.

It is available in tablet form in different composition:

  1. Raxona 375mg
  2. Raxena 500mg
  3. Raxena 750mg

Ranexa used and benefits:

  1. Ranexa is indicated for the treatment of chronic angina (chest pain).
  2. Anti-anginal drugs can be prescribed with other drugs(beta-blockers, nitrates, calcium channel blockers, antiplatelet therapy, lipid-lowering therapy, ACE inhibitors, and angiotensin receptor blockers).

Ranexa Side effects:

If a drug is used to treating some health conditions, along with its benefits there will be some possible side effects too. Adverse effects may not be the same in every individual. But if you see any of them, contact your physician for immediate medical attention.

Below mentioned are some possible side effects of the use of Ranexa are, There may be other side effects too that are not mentioned here. While prescribing your physician will provide proper guidance to avoid adverse side effects.

  • Dizziness
  • Nausea
  • Vomiting
  • Spinning sensation
  • Stomach pain
  • Weakness
  • Ringing in your ears
  • Constipation
  • Headache
  • Dry mouth
  • Swelling in hands/ankles/feet
  • Slow/fast/irregular heartbeats
  • Tremors
  • Blood in the urine
  • Shortness of breath

Ranexa Contraindications:

Most of the drugs may not suitable for everyone and need to be avoided. If not causes adverse effects if used in some health conditions. Notify your Physician if you suffer from any conditions or symptoms.

If the patient is suffering from any heart-related problems Raxena should not be given for example:

  • Narrowing of blood vessels
  • Heart attack
  • Heart rhythm disorders
  • Angina
  • This medicine is also not preferred if the patient is allergic to the ingredients of this medicine

Ranexa Dosage:

Stat dose is given 500 mg to 1000 mg twice daily, depending on the patient condition. Take RANEXA with or without meals. 1 tablet is taken at once, and it should not be crushed, broken, or chewed.

The maximum recommended dose of RANEXA is 1000 mg twice daily.

Ranexa Drug Interactions:

If you take different drugs together there is a chance of drug interaction that results in adverse effects.

If you use other over the counter products or other drugs at the same time, the effects of the Ranexa may change. In such case, the risk of getting side effects might be higher or the effectiveness of the drug may impact. The below-listed drugs are not the complete list. The drug rarely interacts with grapefruit juice.

  • Carbamazepine
  • Cimetidine
  • Rifampicin

Precautions before using Ranexa:

Before using Ranexa, inform your physician if you are under any medications, or using any over the counter products like vitamin supplements, herbal supplements, etc. History of allergies, disease conditions, your current health status, pregnancy, surgery, etc. Inform your Physician so that side effects can be managed. Take the medicine as directed by your physician or follow the directions printed on the leaflet. Dosage is based on your condition and symptoms. Let your physician know if the problem never hinders and continues for a long time or increases.


Taking more than prescribed Ranexa may cause harmful side effects. Consult your physician if you find any side effects. Read the label carefully before taking this medicine to avoid Overdosage. Overdose can result in confusion, headache, fatigue, sedation.

Missing dosage:

If you miss any dose take as soon as you remember. But if the time for next dose, skip the previous dose and continue the regular dose. Avoid taking an extra dose.

Available medicines of Ranexa:

Below mentioned are few substitutes of Raxena. This is not a comprehensive list. This list is for informative purpose only.

  • RANOLAZINE ER 500mg and1000mg


Kiddowell.com provides health-related information on natural products and remedies, prescription medicines, over-the-counter drugs, hospitals and healthcare organizations. The information is provided for educational purposes only. It should not be used as a medical advice, a diagnosis or a suggested treatment.

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