Methocarbamol is a muscle relaxant drug used to treat muscular pains and muscle spasms. It is usually used together with rest and physiotherapy to treat skeletal muscle conditions such as pain or injury. Let’s check out it’s uses, side effects, precautions to be taken before using, drug interaction etc.

How does Methocarbamol work?

It works by helping to relax the muscles. Methocarbamol works by blocking nerve impulses or pain signals that are sent to your brain.

Methocarbamol belongs to a class of medication called muscle relaxants. A class of medication is a group of medications that work in a similar way. These medicines are often used to treat similar conditions. It’s thought that Methocarbamol decreases your body’s messages of pain and slows down your brain (nervous system). This relaxes your muscles and provides pain relief.

Methocarbamol Uses

Methocarbamol is used as an add-on medication to treat musculoskeletal health issues like muscle spasm which include pain.

Methocarbamol used to treat following conditions:

Muscle spasm

Methocarbamol is used to relieve the pain and discomfort associated with muscle spasms which may be caused by muscular injuries or sprains.


Along with other drugs, Methocarbamol is used to treat a bacterial infection which causes painful muscle spasms.

Methocarbamol Side Effects

  • Drowsiness
  • Dizziness
  • Light-headedness
  • Stomach upset
  • Nausea/vomiting
  • Blurred vision

If any of these effects persist or worsen, consult your physician or pharmacist promptly. Inform your physician right away if you have any serious side effects, including fainting, slow heartbeat, yellowing eyes, persistent nausea /vomiting, mood changes (such as confusion, forgetfulness). Remember that your physician has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Methocarbamol Contraindications

Methocarbamol should not be used if you have the following ailments:


This medicine is not recommended for use in patients with a known allergy to Methocarbamol or its ingredients.

Epilepsy or seizures

Methocarbamol in injectable form is not recommended for epileptic patients as there is a possibility of seizures in such cases.

Precautions while using Methocarbamol

If you use other over the counter products or other drugs at the same time, the effects of the Methocarbamol may change and risk of suffering side effects may be high or the drug might not work as intended. Tell your physician about all the medicines, vitamins, and herbal supplements you are using, so that your physician can help you prevent or manage drug interactions. Chance of side effects is more if already suffering any illness that might trigger the side effects. It is advised to follow instructions provided on the leaflet or as directed by your doctor. Dosage is based on your condition. Let your doctor know about the betterment or changes in your condition after using for a while.

Let your doctor know about your medical history in general, particularly if suffering from any condition like epilepsy.

While under medication, it is advised not to indulge in any activity that requires your alertness, as the medication may induce dizziness.

During pregnancy, Methocarbamol should be used only when clearly needed. Discuss the risks and benefits with your doctor. And It is unknown if Methocarbamol passes into breast milk. Consult your physician before breastfeeding.

Methocarbamol Dosage

Methocarbamol available in 2 forms tablet and injectable solution


  • 500mg
  • 750mg

Injectable solution

  • 100mg/mL

Methocarbamol should be taken exactly as directed by your physician. The usual dosage is described below:

The recommended dose is 6 grams/day for the first 2 to 4 days in divided doses. After that, treatment can be continued at 4 grams/day in divided doses.

Methocarbamol Overdose

In case, too many of Methocarbamol have been consumed, rushing to a nearby hospital and seeking help is prudent. If possible, it is also advisable to contact the doctor and ask for advice.  An overdose of Methocarbamol may cause severe dizziness, seizures, drowsiness, loss of consciousness.

Methocarbamol Drug Interactions

Methocarbamol interacts with a number of drugs if taken simultaneously. Hence, you must report to your physician if you are on any of the drugs listed below:

Common drugs checked in combination with Methocarbamol

  • Cymbalta (duloxetine)
  • Celebrex (celecoxib)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • Tylenol (acetaminophen)
  • Ambien (zolpidem)
  • Aspirin Low Strength (aspirin)
  • Benadryl (diphenhydramine)
  • Xanax (alprazolam)
  • Zyrtec (cetirizine)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)

Methocarbamol alcohol Interactions

Consuming alcohol can increase certain side effects of Methocarbamol.

Methocarbamol disease Interactions

There are two disease interactions with Methocarbamol which include:

  • Seizures
  • Renal Dysfunction

Note: It is always advisable to inform your physician about your regular medication list before the prescription of new medications. This can help in eliminating unwarranted side-effects.

Moreover, it is essential to follow the physician’s instructions regarding medicine intake to minimize side-effects.

Disclaimer provides health-related information on natural products and remedies, prescription medicines, over-the-counter drugs, hospitals and healthcare organizations. The information is provided for educational purposes only. It should not be used as a medical advice, a diagnosis or a suggested treatment.

This article was originally published on HealthClues –